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Microdosing Psychedelics

Microdosing began gaining popularity between 2010 and 2013 in Silicon Valley as a way to increase energy and productivity to help brainstorm and tackle road blocks in strategies and coding.

While some people still look to microdosing to help improve their professional efficiency, there are a number of other benefits.

Here are a few of the most common:

  • better focus

  • higher levels of creativity

  • relief from depression

  • more energy

  • less anxiety in social situations

  • emotional openness

  • help quitting coffee, pharmaceutical drugs, or other substances

  • relief from menstrual pain

  • heightened spiritual awareness


People who microdose cannabis claim to be more productive and focused during the workday. It may be a suitable medicine for those looking for anxiety relief.

Cannabidiol (CBD)

Microdosing on CBD is said to potentially promote calm, relieve anxiety, and help with insomnia. CBD is the nonpsychoactive component of the hemp plant.


Nicotine microdosers claim it can help improve concentration, focus, and memory, as well as regulate mood swings.


Everyone’s favorite “upper” may be effective in small doses, too. Some even claim they’re more productive and alert when regularly microdosing caffeine throughout the day versus drinking a full cup of coffee or energy drink. Plus, there’s no crash.

Lysergic acid diethylamide (LSD)

LSD is one of the most popular substances used for microdosing. Some users report feeling sharper, more focused, and more productive throughout the day.

Psilocybin (“Magic” Mushrooms)

Psilocybin may act as an antidepressant for those with major depression. Users have also reported feeling more empathic and emotionally open.

Dimethyltryptamine (DMT)

Known as the “spirit molecule,” microdosed DMT has been said to help relieve anxiety and aid in spiritual awareness.

Steps to Microdosing

Obtaining the medicine.

Psilocybin - Mindful Meds

LSD - Neurodose

DMT - Neurodose

Taking the first dose.

On the morning of a day without any major obligations and without any children present, take the first microdose

Pay attention.

Sit back and observe the experience. You should notice whether or not it matches with your intentions. Keep a log of the day to track the effects. Note: the length of each microdosing experience will vary depending on which substance has been used.

Adjust (if needed).

Did the first time create the desired result? If so, this is the ideal dose. If not, adjust accordingly.

Proceed with regular use.

To start a regimen, follow the “one day on, two days off” principle and continue for up to 10 weeks. This will help avoid building up a tolerance. Building up a tolerance could potentially result in a decrease in the desired results after a few days.

It should be noted that the effects of certain substances can last for up to two days and be detected by blood or urine drug testing a week or more after dosing. Hair follicle testing has a longer detection window, too.

Resources for Microdosing Information:

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